To reproduce the problem:

$./python -m test test_threading -R : -v

...

test_original_excepthook (test.test_threading.ExceptHookTests) ... ok
test_system_exit (test.test_threading.ExceptHookTests) ... ok
test_can_interrupt_tight_loops (test.test_threading.InterruptMainTests) ...

(HANGS here or some time fails like in: 

======================================================================
FAIL: test_can_interrupt_tight_loops (test.test_threading.InterruptMainTests)
----------------------------------------------------------------------
Traceback (most recent call last):
  File "/home/buildbot/buildarea/pull_request.cstratak-RHEL7-ppc64le.refleak/build/Lib/test/support/threading_helper.py", line 62, in decorator
    return func(*args)
           ^^^^^^^^^^^
  File "/home/buildbot/buildarea/pull_request.cstratak-RHEL7-ppc64le.refleak/build/Lib/test/test_threading.py", line 1630, in test_can_interrupt_tight_loops
    self.assertNotEqual(iterations, 0)
    ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
AssertionError: 0 == 0
----------------------------------------------------------------------

https://buildbot.python.org/all/#/builders/411/builds/92